Hivent EM/Hivent DS/Hivent Plus Drug Interactions

Hivent EM: Effect of high doses of salbutamol may be exacerbated by concomitant administration of high doses of corticosteroids.
Salbutamol effects are antagonized by propranolol or other beta-receptor blocking agents.
Concomitant aminophylline or xanthine administration may enhance the salbutamol effects.
Hypokalemia associated with high dose of salbutamol may increase the susceptibility to digitalis-induced cardiac arrhythmias.
Hivent DS: Salbutamol and non-selective β-blocking agents, such as propranolol, should not usually be prescribed together.
Salbutamol is not contraindicated in patients under treatment with monoamine oxidase inhibitors (MAOIs).
Hivent Plus: The effects of ipratropium may be enhanced by concomitant administration of drugs with anticholinergic properties.
Administration of beta₂ adrenoceptor blocking agents antagonizes the effects of beta₂ agonists like salbutamol.
Adverse metabolic effects of high dose of beta₂ agonist may be exacerbated by concomitant administration of high doses of corticosteroids.
Sympathomimetics may antagonize the effects of Antihypertensive agents.
Simultaneous administration with Monoamine Oxidase Inhibitors (MAOIs) will potentiate sympathomimetic activities of beta agonists.
Hypokalemia that may result from the administration of non-potassium sparing diuretics, such as loop and thiazide diuretics, can be acutely worsened by beta agonists, especially when the recommended dose of beta agonist is exceeded.